Publications

9. Erwin GS,*^,† Gursoy G,* Al-Abri R, Suriyaprakash A, Dolzhenko E, Zhu K, Hoerner CH, White SM, Ramirez L, Vadlakonda A, Vadlakonda A, von Kraut K, Park J, Brannon CM, Kirtikar RA, Sumano DA, Erwin AA, Metzner TJ, Yuen RKC, Fan AC, Leppert JT, Eberle MA, Gerstein M,^† Snyder MP^†. Recurrent repeat expansions in human cancer genomes. Nature. Accepted.*equal contribution, ^†Corresponding author

Syn-TEF1 selectively activates frataxin expression in cells from patients with Friedrich ataxia

8. Erwin GS,* Grieshop MP,* Ali A,* Qi J, Lawlor M, Kumar D, Ahmad I, McNally A, Teider N, Worringer K, Sivasankaran R, Eguchi A, Xu M, Srivastava A, Faruq M, Bradner JE, Ansari AZ. Synthetic transcription elongation factors license transcription across repressive heterochromatin. Science 2017, 358, 6370, 1617.*equal contribution

Polyamide binding to specific tandem repeats

7. Erwin GS, Grieshop MP, Bhimsaria D, Do TJ, Rodríguez-Martínez JA, Mehta C, Khanna K, Swanson SA, Stewart R, Thomson JA, Ramanathan P, Ansari AZ. Synthetic genome readers target clustered binding sites across diverse chromatin states. Proceedings of the National Academy of Sciences of the USA 2016, 113, 47, E7418–E7427.

6. Xiong K, Erwin GS, Ansari AZ, Blainey PC. Sliding on DNA: From peptides to small molecules. Angewandte Chemie International Edition. 2016, 55, 48, 15110–15114.

Crosslinking of small molecules to isolate chromatin

5. Erwin GS, Grieshop MP, Bhimsaria D, Eguchi A, Rodríguez-Martínez JA, Ansari AZ. Genome-wide mapping of drug-DNA interactions in cells with COSMIC (crosslinking of small molecules to isolate chromatin). Journal of Visualized Experiments 2016, 107, e53510.

4. Erwin GS, Bhimsaria D, Eguchi A, Ansari AZ. Mapping polyamide−DNA interactions in human cells reveals a new design strategy for effective targeting of genomic sites. Angewandte Chemie International Edition 2014, 53, 10124–10128.
‍Designated Hot Paper

3. Eguchi A, Lee GO, Wan F, Erwin GS, Ansari AZ. Engineering cell fate with precision-targeted DNA-binding proteins and small molecule-based genome readers. Biochemical Journal 2014, 462, 397–413.

Improved myocardial function and viability

2. Erwin GS, Crisostomo PR, Sando IC, Sharma R, Wang M, Markel TA, Guzman M, Sando IC, Sharma R, Meldrum DR. Estradiol treated mesenchymal stem cells improve myocardial recovery after ischemia. Journal of Surgical Research 2009, 152, 2, 319–24.

Female resistance to TNF-induced myocardial depression

1. Sando IC, Wang Y, Crisostomo PR, Markel TA, Sharma R, Erwin GS, Guzman MJ, Meldrum DR, Wang M. Females exhibit relative resistance to the dose-dependent depressive effects of TNF on the myocardium. Journal of Surgical Research 2008, 150, 92–99.